Sheathless capillary electrophoresis-mass spectrometry for anionic metabolic profiling
نویسندگان
چکیده
منابع مشابه
Sheathless capillary electrophoresis‐mass spectrometry for anionic metabolic profiling
The performance of CE coupled on-line to MS via a sheathless porous tip sprayer was evaluated for anionic metabolic profiling. A representative metabolite mixture and biological samples were used for the evaluation of various analytical parameters, such as peak efficiency (plate numbers), migration time and peak area repeatability, and LODs. The BGE, i.e. 10% acetic acid (pH 2.2), previously us...
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A simple procedure was developed for preparing a carbon-coated fused-silica capillary for use in sheathless capillary electrophoresis/electrospray mass spectrometry (CE/ESI-MS). The tapered capillary tip was smeared with a marker pen before coating with carbon using a soft pencil. The layer from the ink of the marker pen was critical to the preparation of the carbon-coated capillary. The fabric...
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A colloidal graphite-coated emitter is introduced for sheathless capillary electrophoresis/nanoelectrospray ionization time-of-flight mass spectrometry (CE/ESI-TOFMS). The conductive coating can be produced by brushing the capillary tip to construct a fine layer of 2-propanol-based colloidal graphite. The fabrication involves a single step and requires less than 2 min. Full cure properties deve...
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This review article addresses the developments and applications of capillary electromigration methods coupled on-line with mass spectrometry for chiral analysis. The multiple enantiomeric applications of this hyphenated technology are covered including chiral analysis of drugs, food compounds, pesticides, natural metabolites, etc., in different matrices such as plasma, urine, medicines, foods, ...
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ژورنال
عنوان ژورنال: ELECTROPHORESIS
سال: 2015
ISSN: 0173-0835
DOI: 10.1002/elps.201500435